Crime is an overhead you have to pay if you want to live in the city.
Meaning of the quote
The quote means that when you live in a city, you have to deal with some bad things like crime, even though you don't want to. It's like a cost or fee you have to pay to live in the city, just like you have to pay for other things like rent or food. The quote suggests that crime is a normal part of city life, even though it's not a good thing.
About George Moscone
George Moscone was the 37th mayor of San Francisco, known as “The People’s Mayor” for his efforts to make City Hall more diverse and inclusive. He served in the California State Senate before becoming mayor, where he was remembered as an advocate of civil progressivism.