I hate people who think it’s clever to take drugs… like custom officers.

Meaning of the quote

This quote is making a joke about people who try to sneak illegal drugs past customs officials. The comedian is saying that he dislikes people who think it's clever or smart to use drugs, especially when they try to hide or smuggle them through customs. The joke is that the custom officers, whose job is to catch people bringing in drugs, are also using drugs themselves. This is meant to be a humorous, ironic statement about the people who try to break the law by bringing in illegal substances.